IMPDH1P11

Across TCGA pan-cancer cohorts, IMPDH1P11 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated IMPDH1P11 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher IMPDH1P11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IMPDH1P11 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SARC show a favorable association.

STAD, BRCA, and HNSC are the cancer types where IMPDH1P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.295	0.625	.001	44	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	37	view →
HNSC	DFS	Median	II,III,IV	0.496	0.259	.003	34	view →
KIRC	DFS	Quartile	All	0.453	0.674	.006	24	view →
UCS	OS	Quartile	II,III,IV	0.161	0.568	.008	18	view →
THCA	OS	Tertile	IV	0.514	0.924	.001	13	view →
THYM	OS	Tertile	All	0.635	0.892	.023	12	view →
LIHC	DFS	Tertile	All	0.188	0.306	.034	12	view →
ACC	DFS	Tertile	III,IV	0.231	0.508	.043	9	view →
LUSC	DFS	Quartile	III,IV	0.382	0.787	.028	6	view →
READ	OS	Median	IV	0.531	0.857	.036	4	view →
KIRP	DFS	Tertile	All	0.785	0.874	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

IMPDH1P11–STAD (DFS)

Open the STAD breakdown →