IMPDH1P10

Across TCGA pan-cancer cohorts, IMPDH1P10 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated IMPDH1P10 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher IMPDH1P10 RNA is associated with better overall survival. In most high-consensus cancer types, elevated IMPDH1P10 expression acts as an unfavorable survival marker, although some lineages such as BLCA and ESCA show a favorable association.

BLCA, LGG, and ESCA are the cancer types where IMPDH1P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Quartile	IV	0.731	0.456	.001	96	view →
LGG	DFS	Quartile	All	0.594	0.757	<.001	30	view →
ESCA	DFS	Median	All	0.573	0.421	.021	23	view →
HNSC	DFS	Median	IV	0.448	0.261	.008	22	view →
UCEC	OS	Tertile	IV	0.593	0.249	.023	22	view →
PRAD	DFS	Median	All	0.696	0.819	<.001	20	view →
READ	OS	Tertile	All	0.814	0.965	.009	17	view →
BRCA	OS	Median	IV	0.965	0.579	.010	14	view →
KIRC	DFS	Median	IV	0.245	0.415	.022	12	view →
LIHC	DFS	Quartile	All	0.365	0.476	.019	10	view →
LUAD	DFS	Tertile	II,III,IV	0.090	0.435	.008	9	view →
UVM	OS	Tertile	III,IV	0.204	0.707	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

IMPDH1P10–BLCA (OS)

Open the BLCA breakdown →