IMPDH1

Across TCGA patient cohorts, IMPDH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,338 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IMPDH1-associated proteins across cancer lineages are TNPO3, SMC2, and CUL1. Each is linked with IMPDH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IMPDH1-to-partner and partner-to-IMPDH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPDH1 versus TNPO3 in CCRCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPDH1→partner) and Y-score (partner→IMPDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TNPO3 →	+0.297	+0.642	<.001	<.001	3	7
GBM	SMC2 →	+0.562	+0.434	<.001	<.001	3	6
HNSC	CUL1 →	+0.248	+0.988	<.001	<.001	3	6
LUAD	RRP36_S73 →	+0.683	+0.626	<.001	<.001	3	5
LUAD	SCLY →	-0.318	-0.571	.002	.002	3	5
LUAD	PITPNC1_S299 →	-0.488	-0.594	.007	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,338 associations by consensus.

IMPDH1 vs TNPO3 — CCRCC

Explore this scatter interactively →