IMPA2

Across TCGA patient cohorts, IMPA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,018 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IMPA2-associated proteins across cancer lineages are PTPN2_S304, RBM47, and NCAPD2. Each is linked with IMPA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both IMPA2-to-partner and partner-to-IMPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPA2 versus PTPN2_S304 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPA2→partner) and Y-score (partner→IMPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPN2_S304 →	+0.846	+1.006	<.001	<.001	3	6
GBM	RBM47 →	+0.423	+0.538	<.001	<.001	3	5
BRCA	NCAPD2 →	+0.638	+1.240	<.001	<.001	3	5
LSCC	NFKBIE →	-0.284	-0.943	<.001	<.001	3	5
HNSC	PANK4 →	-0.192	-0.657	.001	<.001	3	5
COAD	RRM1 →	+0.445	+0.545	.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,018 associations by consensus.

IMPA2 vs PTPN2_S304 — BRCA

Explore this scatter interactively →