IMPA2

Across TCGA cell cohorts, IMPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,698 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IMPA2-associated GO terms across cancer lineages are Response to lithium ion, Inositol biosynthetic process, and Inositol metabolic process. Each is linked with IMPA2 in more than 14 cancer types. Because this analysis shows association rather than direction, both IMPA2-to-partner and partner-to-IMPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to lithium ion grouped by IMPA2-low versus IMPA2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPA2→partner) and Y-score (partner→IMPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Response to lithium ion →	+0.326	+2.746	<.001	<.001	3	15
BONE	Inositol biosynthetic process →	+0.292	+1.772	<.001	<.001	3	14
LUNG_SCLC	Inositol metabolic process →	+0.219	+1.950	<.001	<.001	3	12
BLOOD_Myeloma	Mitotic DNA replication →	+0.153	+2.006	<.001	.007	3	9
BONE	Positive regulation of vasculature development →	-0.123	-1.254	<.001	.002	3	9
SOFT_TISSUE	Regulation of leukocyte apoptotic process →	-0.122	-1.752	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,698 associations by consensus.

Response to lithium ion by IMPA2 expression — KIDNEY

Explore this box plot interactively →