IMPA1

Across TCGA patient cohorts, IMPA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,956 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IMPA1-associated proteins across cancer lineages are YTHDF3, CPNE3, and LACTB2. Each is linked with IMPA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both IMPA1-to-partner and partner-to-IMPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPA1 versus YTHDF3 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPA1→partner) and Y-score (partner→IMPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	YTHDF3 →	+0.253	+0.511	.001	<.001	3	4
OV	CPNE3 →	+0.634	+0.810	<.001	<.001	3	4
OV	LACTB2 →	+0.454	+0.567	.003	.004	3	3
OV	NBN →	+0.390	+0.582	<.001	.001	3	3
OV	ARFGEF1 →	+0.399	+0.606	<.001	.001	2	4
BRCA	RASIP1_S90 →	+1.401	+1.054	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,956 associations by consensus.

IMPA1 vs YTHDF3 — LUAD

Explore this scatter interactively →