IMPA1

Across TCGA cell cohorts, IMPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,368 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IMPA1-associated GO terms across cancer lineages are Centriole-centriole cohesion, DNA synthesis involved in DNA repair, and Blastocyst growth. Each is linked with IMPA1 in more than 10 cancer types. Because this analysis shows association rather than direction, both IMPA1-to-partner and partner-to-IMPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole-centriole cohesion grouped by IMPA1-low versus IMPA1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPA1→partner) and Y-score (partner→IMPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Centriole-centriole cohesion →	+0.103	+1.096	.001	<.001	3	11
LUNG_NSCLC_LUSC	DNA synthesis involved in DNA repair →	+0.120	+1.560	.001	.001	3	11
LARGE_INTESTINE	Blastocyst growth →	+0.198	+0.981	<.001	<.001	3	11
BREAST	DNA biosynthetic process →	+0.072	+1.354	<.001	<.001	3	11
SKIN	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.085	+0.413	.001	.009	3	11
OVARY	7-methylguanosine mRNA capping →	+0.083	+0.662	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,368 associations by consensus.

Centriole-centriole cohesion by IMPA1 expression — STOMACH

Explore this box plot interactively →