IMP4

Across TCGA cell cohorts, IMP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,654 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IMP4-associated GO terms across cancer lineages are rRNA metabolic process, Ribosomal small subunit biogenesis, and Transcription initiation at RNA polymerase I promoter. Each is linked with IMP4 in more than 16 cancer types. Because this analysis shows association rather than direction, both IMP4-to-partner and partner-to-IMP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by IMP4-low versus IMP4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMP4→partner) and Y-score (partner→IMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	rRNA metabolic process →	+0.114	+1.125	<.001	<.001	3	17
BONE	Ribosomal small subunit biogenesis →	+0.129	+0.999	.001	.002	3	17
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase I promoter →	+0.153	+0.711	.001	.005	3	17
BONE	rRNA processing →	+0.135	+0.882	.001	.005	3	17
URINARY_TRACT	Nucleolar large rRNA transcription by RNA polymerase I →	+0.117	+0.720	<.001	.002	3	17
URINARY_TRACT	Mitochondrial large ribosomal subunit assembly →	+0.130	+1.056	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,654 associations by consensus.

rRNA metabolic process by IMP4 expression — URINARY_TRACT

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