IMP3P2

Across TCGA pan-cancer cohorts, IMP3P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of IMP3P2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where IMP3P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IMP3P2 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUSC, BRCA, and COAD are the cancer types where IMP3P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IMP3P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	III,IV	+0.172	<.001	6	view →
BRCA	Female	All	+0.056	.030	2	view →
COAD	Female	All	+0.106	.038	1	view →
KIRC	Male	All	−0.025	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

IMP3P2–LUSC

Open the LUSC breakdown →