IMMT

Across TCGA pan-cancer cohorts, IMMT mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated IMMT data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher IMMT mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IMMT expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where IMMT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.013	78	view →
CCRCC	DFS	Median	II,III,IV	0.527	0.874	.001	28	view →
PDAC	OS	Median	All	0.615	0.343	.001	21	view →
HNSC	OS	Median	II,III,IV	0.932	0.992	.019	3	view →
LSCC	DFS	Tertile	All	0.631	1.000	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

IMMT–COAD (DFS)

Open the COAD breakdown →