IMMT

Across TCGA patient cohorts, IMMT RNA expression is significantly associated with the protein abundance of many other proteins, with 19,082 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IMMT-associated proteins across cancer lineages are RRM2, RRM2_S20, and SMC2. Each is linked with IMMT in more than 7 cancer types. Because this analysis shows association rather than direction, both IMMT-to-partner and partner-to-IMMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMMT versus RRM2 in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMMT→partner) and Y-score (partner→IMMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.740	+0.595	<.001	<.001	3	7
UCEC	RRM2_S20 →	+0.932	+0.434	.001	.003	2	8
GBM	SMC2 →	+0.673	+0.279	<.001	<.001	3	7
LUAD	MCM2 →	+0.678	+0.276	<.001	<.001	3	7
LSCC	MCM3 →	+0.670	+0.574	<.001	<.001	3	7
LSCC	MCM4 →	+0.670	+0.578	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,082 associations by consensus.

IMMT vs RRM2 — UCEC

Explore this scatter interactively →