IMMT

Across TCGA patient cohorts, IMMT protein abundance is significantly associated with the protein abundance of many other proteins, with 27,389 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IMMT-associated proteins across cancer lineages are IARS2, APOO, and COX4I1. Each is linked with IMMT in more than 9 cancer types. Because this analysis shows association rather than direction, both IMMT-to-partner and partner-to-IMMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMMT versus IARS2 in OV, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMMT→partner) and Y-score (partner→IMMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IARS2 →	+0.412	+0.209	<.001	<.001	3	10
UCEC	APOO →	+0.711	+0.446	<.001	<.001	3	10
UCEC	COX4I1 →	+0.875	+0.503	<.001	<.001	3	10
UCEC	COX5B →	+0.479	+0.378	<.001	<.001	3	10
UCEC	COX6C →	+0.823	+0.452	<.001	<.001	3	10
UCEC	CS →	+0.374	+0.399	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,389 associations by consensus.

IMMT vs IARS2 — OV

Explore this scatter interactively →