IMMT

Across TCGA cell cohorts, IMMT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,692 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IMMT-associated GO terms across cancer lineages are DNA replication initiation, Defense response to bacterium, and DNA-templated DNA replication. Each is linked with IMMT in more than 14 cancer types. Because this analysis shows association rather than direction, both IMMT-to-partner and partner-to-IMMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by IMMT-low versus IMMT-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMMT→partner) and Y-score (partner→IMMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.181	+0.989	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.112	-0.767	.002	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.095	+0.766	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid cohesion →	+0.105	+0.980	.001	<.001	3	14
PANCREAS	Spindle elongation →	+0.217	+0.529	<.001	.001	3	14
BLOOD_Lymphoma	DNA strand elongation →	+0.137	+0.836	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,692 associations by consensus.

DNA replication initiation by IMMT expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →