Across TCGA patient cohorts, IMMP2L mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IMMP2L-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and JNK2. Each is linked with IMMP2L in more than 1 cancer types. Because this analysis shows association rather than direction, both IMMP2L-to-partner and partner-to-IMMP2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMMP2L→partner) and Y-score (partner→IMMP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.314	-2.584	.007	.011	3	1
UCEC	A-Raf_pS299 →	-0.123	-3.000	.026	.036	3	1
UCEC	JNK2 →	+0.269	+2.331	.003	.019	3	1
UCEC	Ku80 →	+0.260	+1.887	.018	.031	3	1
UCEC	MEK1 →	+0.339	+2.321	.047	.034	3	1
UCEC	Notch1 →	+0.221	+3.179	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

IMMP2L survival (RNA) · tumor vs normal (RNA) · all IMMP2L data types