IMMP1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IMMP1L mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IMMP1L-associated genes across cancer lineages are RNU6-929P, RNA5SP497, and CNGA2. Each is linked with IMMP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both IMMP1L-to-partner and partner-to-IMMP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-929P grouped by IMMP1L-low versus IMMP1L-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMMP1L→partner) and Y-score (partner→IMMP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-929P →+0.368+7.741<.001.00932
UCECRNA5SP497 →+0.652+3.771<.001.00232
HNSCCNGA2 →+0.040+5.015<.001.00931
HNSCRNU6-707P →+0.425+6.339<.001.00131
HNSCRNA5SP259 →+0.367+5.655<.001.00431
HNSCSNORA36A →+0.325+5.241<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

RNU6-929P by IMMP1L expression — COAD

Box plot of RNU6-929P in IMMP1L-low vs IMMP1L-high samples in COAD.

Explore this box plot interactively →

Exploration