Across TCGA patient cohorts, ILRUN protein abundance is significantly associated with the RNA expression of many other genes, with 4,468 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ILRUN-associated genes across cancer lineages are DISC1, F13A1, and MYH11. Each is linked with ILRUN in more than 2 cancer types. Because this analysis shows association rather than direction, both ILRUN-to-partner and partner-to-ILRUN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILRUN→partner) and Y-score (partner→ILRUN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DISC1 →	-0.503	-0.178	<.001	.001	3	3
BRCA	F13A1 →	-0.949	-0.159	.004	.009	3	3
OV	MYH11 →	-1.192	-0.628	.005	<.001	3	3
BRCA	HMCN1 →	-1.036	-0.229	<.001	.001	3	3
PDAC	RPUSD3 →	-0.261	-0.250	<.001	<.001	3	3
BRCA	ANTXR2 →	-0.467	-0.216	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,468 associations by consensus.

Exploration

ILRUN survival (RNA) · tumor vs normal (RNA) · all ILRUN data types