ILKAP

Across TCGA pan-cancer cohorts, ILKAP RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ILKAP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ILKAP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ILKAP is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

COAD, KICH, and LIHC are the cancer types where ILKAP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ILKAP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.916	<.001	11	view →
KICH	Female	II,III,IV	−1.457	<.001	9	view →
LIHC	Male	II,III,IV	+0.859	<.001	9	view →
HNSC	Male	All	+0.590	<.001	8	view →
READ	All	All	+0.435	<.001	7	view →
CHOL	Male	All	+1.848	<.001	5	view →
STAD	All	II,III,IV	+0.529	<.001	4	view →
ESCA	All	All	+0.748	.001	3	view →
LUAD	Male	II,III,IV	+0.340	.024	3	view →
LUSC	Male	All	+0.343	<.001	2	view →
UCEC	All	II,III,IV	+0.328	.032	2	view →
BLCA	Male	IV	−0.545	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ILKAP–COAD

Open the COAD breakdown →