ILK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ILK protein abundance is significantly associated with the RNA expression of many other genes, with 21,649 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ILK-associated genes across cancer lineages are MYL9, SRPX, and SYDE1. Each is linked with ILK in more than 9 cancer types. Because this analysis shows association rather than direction, both ILK-to-partner and partner-to-ILK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ILK versus MYL9 in COAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILK→partner) and Y-score (partner→ILK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMYL9 →+1.389+0.450<.001<.001310
BRCASRPX →+1.453+0.489<.001<.001310
BRCASYDE1 →+0.863+0.476<.001<.001310
OVACTA2 →+2.025+0.445<.001<.001310
BRCACALD1 →+1.241+0.556<.001<.001310
CCRCCISLR →+1.981+0.404<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,649 associations by consensus.

ILK vs MYL9 — COAD

Per-sample scatter of ILK vs MYL9 in COAD (Pearson r = 0.65).

Explore this scatter interactively →

Exploration