ILK

Across TCGA patient cohorts, ILK mutation is significantly associated with the RNA expression of many other genes, with 1,385 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILK-associated genes across cancer lineages are RNVU1-28, SNRPGP6, and RNU6-1067P. Each is linked with ILK in more than 2 cancer types. Because this analysis shows association rather than direction, both ILK-to-partner and partner-to-ILK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-28 grouped by ILK-low versus ILK-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILK→partner) and Y-score (partner→ILK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNVU1-28 →	+0.301	+4.296	.003	.008	3	3
CESC	SNRPGP6 →	+0.105	+4.837	<.001	.003	3	2
SKCM	RNU6-1067P →	+0.555	+4.500	<.001	.005	3	2
CESC	RNU6-1208P →	+0.241	+3.684	<.001	.005	3	2
HNSC	BNIP3P41 →	+0.024	+7.954	<.001	.008	3	2
HNSC	MIR8075 →	+0.268	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,385 associations by consensus.

RNVU1-28 by ILK expression — SKCM

Explore this box plot interactively →