ILF3

Across TCGA pan-cancer cohorts, ILF3 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ILF3 data layer compared with 24 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ILF3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ILF3 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

HNSC, COAD, and LSCC are the cancer types where ILF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	IV	0.559	0.950	<.001	74	view →
COAD	DFS	Median	All	1.000	0.918	.012	60	view →
LSCC	DFS	Median	II,III,IV	0.842	0.563	.007	23	view →
OV	DFS	Quartile	All	0.579	1.000	.014	12	view →
UCEC	OS	Quartile	All	0.902	1.000	.022	6	view →
GBM	OS	Quartile	All	0.681	0.422	.037	4	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.856	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ILF3–HNSC (OS)

Open the HNSC breakdown →