ILF3

Across TCGA patient cohorts, ILF3 mutation is significantly associated with the RNA expression of many other genes, with 5,103 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILF3-associated genes across cancer lineages are SSRP1, CHEK1, and MRPL39. Each is linked with ILF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ILF3-to-partner and partner-to-ILF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSRP1 grouped by ILF3-low versus ILF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILF3→partner) and Y-score (partner→ILF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SSRP1 →	+0.332	+1.617	.009	.005	3	3
UCEC	CHEK1 →	+0.639	+3.480	<.001	<.001	3	3
UCEC	MRPL39 →	+0.355	+1.595	<.001	<.001	3	3
COAD	PPP4R1 →	+0.594	+3.727	<.001	<.001	3	3
UCEC	CCT8 →	+0.342	+1.946	.001	<.001	3	3
UCEC	EXOG →	+0.346	+2.233	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,103 associations by consensus.

SSRP1 by ILF3 expression — UCEC

Explore this box plot interactively →