ILF3

Across TCGA patient cohorts, ILF3 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILF3-associated genes across cancer lineages are Caspase-7-cleavedD198, ASNS, and p38-MAPK_pT180_Y182. Each is linked with ILF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ILF3-to-partner and partner-to-ILF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ILF3-low versus ILF3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILF3→partner) and Y-score (partner→ILF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.610	+2.189	.001	.001	3	5
COAD	ASNS →	+0.755	+2.178	<.001	.035	3	5
UCEC	p38-MAPK_pT180_Y182 →	-0.350	-1.662	.013	.010	3	3
UCEC	PDCD4 →	-0.696	-1.836	<.001	.001	3	3
UCEC	TIGAR →	+0.110	+1.611	.022	.003	3	3
UCEC	ATM →	-0.399	-1.687	.005	.040	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Caspase-7-cleavedD198 by ILF3 expression — UCEC

Explore this box plot interactively →