ILF2

Across TCGA patient cohorts, ILF2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILF2-associated genes across cancer lineages are Caspase-8, MEK1, and Paxillin. Each is linked with ILF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ILF2-to-partner and partner-to-ILF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by ILF2-low versus ILF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILF2→partner) and Y-score (partner→ILF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.431	-3.143	.001	.018	3	2
UCEC	MEK1 →	+0.415	+3.169	.038	.020	3	1
UCEC	Paxillin →	+0.338	+2.817	.017	.036	3	1
UCEC	Tuberin →	+0.585	+3.009	<.001	.019	3	1
UCEC	VHL →	-1.402	-3.169	<.001	.019	3	1
UCEC	CD49b →	-0.356	-2.980	.022	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Caspase-8 by ILF2 expression — UCEC

Explore this box plot interactively →