ILF2

Across TCGA cell cohorts, ILF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,706 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ILF2-associated GO terms across cancer lineages are DNA replication, Mitotic sister chromatid cohesion, and Cell cycle checkpoint signaling. Each is linked with ILF2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ILF2-to-partner and partner-to-ILF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by ILF2-low versus ILF2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ILF2→partner) and Y-score (partner→ILF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication →	+0.086	+0.552	<.001	<.001	3	18
SOFT_TISSUE	Mitotic sister chromatid cohesion →	+0.103	+0.703	<.001	<.001	3	18
SOFT_TISSUE	Cell cycle checkpoint signaling →	+0.100	+1.065	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cell cycle phase transition →	+0.080	+1.241	<.001	<.001	3	17
LIVER	DNA-templated DNA replication →	+0.093	+0.744	.002	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication →	+0.213	+1.270	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,706 associations by consensus.

DNA replication by ILF2 expression — PANCREAS

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