ILDR2

Across TCGA cell cohorts, ILDR2 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ILDR2-associated genes across cancer lineages are ODF1, REG1B, and EXOC1L. Each is linked with ILDR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ILDR2-to-partner and partner-to-ILDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by ILDR2-low versus ILDR2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILDR2→partner) and Y-score (partner→ILDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ODF1 →	+0.016	+4.437	<.001	.004	3	2
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	2
LUNG_NSCLC_LUSC	EXOC1L →	+0.063	+4.643	<.001	.008	3	1
UPPER_AERODIGESTIVE_TRACT	C4orf50 →	+0.013	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	TRIM77 →	+0.030	+5.357	<.001	.003	3	1
LARGE_INTESTINE	PRSS54 →	+0.042	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

ODF1 by ILDR2 expression — SKIN

Explore this box plot interactively →