Across TCGA pan-cancer cohorts, IL9RP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of IL9RP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IL9RP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IL9RP1 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.
KIRC and LUAD are the cancer types where IL9RP1 tumor–normal differential expression is most reproducible.