IL9

Across TCGA patient cohorts, IL9 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IL9-associated genes across cancer lineages are OOSP1P1, CRYGA, and MIR1285-2. Each is linked with IL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL9-to-partner and partner-to-IL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP1P1 grouped by IL9-low versus IL9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL9→partner) and Y-score (partner→IL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OOSP1P1 →	+0.209	+4.680	<.001	.007	3	2
SKCM	CRYGA →	+0.098	+4.628	.003	.004	3	2
SKCM	MIR1285-2 →	+0.411	+5.080	<.001	.004	3	2
UCEC	MIR98 →	+0.408	+3.801	.001	.004	3	1
SKCM	RN7SL478P →	+0.385	+4.531	<.001	.005	3	1
SKCM	SLC25A3P1 →	+0.028	+4.381	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

OOSP1P1 by IL9 expression — SKCM

Explore this box plot interactively →