IL7

Across TCGA patient cohorts, IL7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,838 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL7-associated proteins across cancer lineages are IFI35, CASP1, and CD74. Each is linked with IL7 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL7-to-partner and partner-to-IL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL7 versus IFI35 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL7→partner) and Y-score (partner→IL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFI35 →	+0.522	+0.645	<.001	.001	3	8
BRCA	CASP1 →	+0.562	+0.661	<.001	<.001	3	7
HNSC	CD74 →	+0.874	+0.990	<.001	<.001	3	7
BRCA	GBP4 →	+0.839	+0.635	<.001	<.001	3	7
HNSC	TRIM21 →	+0.445	+0.607	<.001	<.001	3	6
HNSC	PSMB10 →	+0.777	+1.136	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,838 associations by consensus.

IL7 vs IFI35 — HNSC

Explore this scatter interactively →