IL6RP1

Across TCGA pan-cancer cohorts, IL6RP1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated IL6RP1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher IL6RP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IL6RP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

BLCA, THYM, and HNSC are the cancer types where IL6RP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.051	0.600	<.001	63	view →
THYM	DFS	Tertile	III,IV	0.205	0.774	.007	45	view →
HNSC	OS	Tertile	All	0.933	0.377	.024	33	view →
KIRC	DFS	Tertile	IV	0.208	0.545	.004	24	view →
CESC	OS	Tertile	II,III,IV	0.285	0.763	.048	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
PCPG	DFS	Tertile	All	0.482	0.913	<.001	18	view →
UCS	DFS	Tertile	II,III,IV	0.828	0.292	.024	12	view →
READ	DFS	Tertile	III,IV	0.269	0.744	.025	9	view →
KICH	OS	Tertile	All	0.892	0.970	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

IL6RP1–BLCA (OS)

Open the BLCA breakdown →