IL5RA

Across TCGA pan-cancer cohorts, IL5RA Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated IL5RA data layer compared with 24 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher IL5RA Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL5RA expression acts as an unfavorable survival marker.

ESCA, UCEC, and SKCM are the cancer types where IL5RA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	III,IV	0.100	0.442	.003	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	III,IV	0.121	0.654	.004	6	view →
LUSC	DFS	Median	All	0.421	0.651	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

IL5RA–ESCA (DFS)

Open the ESCA breakdown →