IL5RA

Across TCGA patient cohorts, IL5RA protein abundance is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL5RA-associated genes across cancer lineages are USP31, LIPA, and ERBIN. Each is linked with IL5RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL5RA-to-partner and partner-to-IL5RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL5RA versus USP31 in LSCC, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL5RA→partner) and Y-score (partner→IL5RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	USP31 →	-1.023	-0.940	.006	.008	3	1
LSCC	LIPA →	+0.598	+0.727	.008	.009	3	1
LSCC	ERBIN →	+0.286	+0.728	.007	.009	3	1
LSCC	TBC1D20 →	-0.793	-1.133	.001	.006	3	1
LSCC	FOXJ1 →	+4.170	+1.133	<.001	.006	3	1
LSCC	COQ3 →	-0.793	-0.728	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

IL5RA vs USP31 — LSCC

Explore this scatter interactively →