IL5RA

Across TCGA cell cohorts, IL5RA RNA expression is significantly associated with the go_rna of many other GO terms, with 1,078 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible IL5RA-associated GO terms across cancer lineages are SNARE complex assembly, Regulation of vasoconstriction, and Regulation of macroautophagy. Each is linked with IL5RA in more than 3 cancer types. Because this analysis shows association rather than direction, both IL5RA-to-partner and partner-to-IL5RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNARE complex assembly grouped by IL5RA-low versus IL5RA-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL5RA→partner) and Y-score (partner→IL5RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SNARE complex assembly →	+0.084	+0.012	<.001	.001	3	4
LUNG_SCLC	Regulation of vasoconstriction →	-0.065	-0.471	<.001	.003	3	4
BLOOD_Leukemia	Regulation of macroautophagy →	+0.028	+0.409	<.001	.004	3	4
LUNG_SCLC	Positive regulation of telomerase RNA localization to Cajal body →	+0.051	+0.494	.007	.001	3	4
LUNG_SCLC	Blood vessel morphogenesis →	-0.037	-0.498	.001	.001	3	4
LUNG_SCLC	Cardiac muscle tissue regeneration →	-0.764	-0.458	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,078 associations by consensus.

SNARE complex assembly by IL5RA expression — LUNG_NSCLC_LUAD

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