IL3RA

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IL3RA Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL3RA data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IL3RA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IL3RA expression acts as an unfavorable survival marker.

LUAD, READ, and COAD are the cancer types where IL3RA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianII,III,IV0.3010.683.00710view →
READOSMedianAll0.2810.830.0063view →
COADOSMedianAll0.6710.873.0491view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration