Across TCGA pan-cancer cohorts, IL3RA mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated IL3RA data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL3RA mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IL3RA expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LUAD, and CCRCC are the cancer types where IL3RA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	1.000	0.534	.023	26	view →
LUAD	OS	Quartile	II,III,IV	0.878	0.469	.022	6	view →
CCRCC	DFS	Median	All	1.000	0.575	.027	2	view →
LSCC	DFS	Quartile	All	0.888	1.000	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: IL3RA tumor-vs-normal RNA expression · all IL3RA data types