IL3RA

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL3RA mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL3RA-associated genes across cancer lineages are 14-3-3_beta, MSH2, and PCNA. Each is linked with IL3RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL3RA-to-partner and partner-to-IL3RA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL3RA→partner) and Y-score (partner→IL3RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.085-2.558.016.01032
UCECMSH2 →-0.172-3.558.034.00232
UCECPCNA →+0.197+3.807.009<.00132
UCECPKC-delta_pS664 →-0.100-2.000.018.02932
UCECShc_pY317 →-0.149-1.362.005.03732
UCECTFRC →+0.477+2.584.010.01032
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

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