IL36G

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IL36G Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL36G data layer compared with 21 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher IL36G Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL36G expression acts as an unfavorable survival marker.

UCS, LIHC, and GBM are the cancer types where IL36G Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSDFSMedianAll0.0680.524<.00148view →
LIHCOSMedianAll0.1440.688.0139view →
GBMDFSMedianAll0.0640.257.0146view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IL36G–UCS (DFS)

Kaplan–Meier survival curve for IL36G mutant vs wild-type samples in UCS.

Open the UCS breakdown →

Exploration