IL36G

Across TCGA pan-cancer cohorts, IL36G mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL36G data layer compared with 21 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL36G mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IL36G expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, LSCC, and UCEC are the cancer types where IL36G mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.748	0.538	.006	31	view →
LSCC	OS	Median	All	1.000	0.919	.009	12	view →
UCEC	DFS	Median	All	1.000	0.682	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IL36G–HNSC (DFS)

Open the HNSC breakdown →