IL36G

Across TCGA cell cohorts, IL36G RNA expression is significantly associated with the go_rna of many other GO terms, with 1,466 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible IL36G-associated GO terms across cancer lineages are Leukocyte aggregation, Viral gene expression, and Negative regulation of DNA-templated transcription initiation. Each is linked with IL36G in more than 8 cancer types. Because this analysis shows association rather than direction, both IL36G-to-partner and partner-to-IL36G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukocyte aggregation grouped by IL36G-low versus IL36G-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL36G→partner) and Y-score (partner→IL36G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Leukocyte aggregation →	+0.274	+0.500	.001	.007	3	8
OVARY	Viral gene expression →	+0.043	+0.253	.006	.006	2	9
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.120	+0.297	.009	.002	3	7
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.120	+0.297	.009	.002	3	7
URINARY_TRACT	Regulation of cell adhesion molecule production →	+0.746	+1.198	.005	.005	3	6
SKIN	Positive regulation of protein import into nucleus →	+0.068	+0.596	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,466 associations by consensus.

Leukocyte aggregation by IL36G expression — LUNG_NSCLC_LUAD

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