IL36B

Across TCGA patient cohorts, IL36B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,738 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IL36B-associated proteins across cancer lineages are IL1RN, AHNAK2_S842, and PLOD2. Each is linked with IL36B in more than 4 cancer types. Because this analysis shows association rather than direction, both IL36B-to-partner and partner-to-IL36B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL36B versus IL1RN in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL36B→partner) and Y-score (partner→IL36B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IL1RN →	+0.903	+0.369	<.001	<.001	3	4
GBM	AHNAK2_S842 →	+0.775	+0.185	<.001	.008	3	4
GBM	PLOD2 →	+0.785	+0.284	<.001	<.001	3	4
GBM	TRIP10 →	+0.407	+0.305	<.001	<.001	3	4
GBM	SERPINH1 →	+0.619	+0.325	<.001	<.001	3	4
HNSC	GIMAP7 →	-0.502	-0.793	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,738 associations by consensus.

IL36B vs IL1RN — LSCC

Explore this scatter interactively →