IL3

Across TCGA patient cohorts, IL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,183 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IL3-associated GO terms across cancer lineages are CD4-positive, alpha-beta T cell activation, B cell activation, and Regulation of cysteine-type endopeptidase activity involved in apoptotic process. Each is linked with IL3 in more than 8 cancer types. Because this analysis shows association rather than direction, both IL3-to-partner and partner-to-IL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4-positive, alpha-beta T cell activation grouped by IL3-low versus IL3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL3→partner) and Y-score (partner→IL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CD4-positive, alpha-beta T cell activation →	+0.026	+0.056	.001	.001	3	9
STAD	B cell activation →	+0.039	+0.072	<.001	<.001	3	8
STAD	Regulation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.039	+0.041	<.001	<.001	3	8
STAD	Regulation of myeloid leukocyte mediated immunity →	+0.031	+0.073	<.001	<.001	3	8
TGCT	Immune response-regulating cell surface receptor signaling pathway involved in phagocytosis →	+0.056	+0.153	<.001	<.001	3	8
STAD	Positive regulation of peptidase activity →	+0.036	+0.041	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,183 associations by consensus.

CD4-positive, alpha-beta T cell activation by IL3 expression — STAD

Explore this box plot interactively →