IL3

Across TCGA cell cohorts, IL3 RNA expression is significantly associated with the mutation status of many other genes, with 157 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible IL3-associated genes across cancer lineages are GNPTAB, COL6A5, and CHL1. Each is linked with IL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL3-to-partner and partner-to-IL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNPTAB grouped by IL3-low versus IL3-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL3→partner) and Y-score (partner→IL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GNPTAB →	+4.369	+0.054	.008	<.001	3	2
SOFT_TISSUE	COL6A5 →	+3.954	+0.035	<.001	<.001	3	2
URINARY_TRACT	CHL1 →	+4.087	+0.020	.009	<.001	3	2
URINARY_TRACT	POLE →	+4.087	+0.020	.009	<.001	3	2
BLOOD_Myeloma	MATN4 →	+4.807	+0.020	.006	<.001	3	2
LUNG_NSCLC_LUSC	EXPH5 →	+4.643	+0.020	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

GNPTAB by IL3 expression — SOFT_TISSUE

Explore this box plot interactively →