IL26

Across TCGA cell cohorts, IL26 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,102 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IL26-associated GO terms across cancer lineages are Negative regulation of lymphocyte mediated immunity, Phospholipid transfer to membrane, and Metabolic compound salvage. Each is linked with IL26 in more than 3 cancer types. Because this analysis shows association rather than direction, both IL26-to-partner and partner-to-IL26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lymphocyte mediated immunity grouped by IL26-low versus IL26-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL26→partner) and Y-score (partner→IL26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of lymphocyte mediated immunity →	-0.127	-0.027	.002	.008	3	4
BLOOD_Lymphoma	Phospholipid transfer to membrane →	-0.093	-2.723	.002	.001	3	4
CNS	Metabolic compound salvage →	-0.047	-0.046	<.001	.001	3	3
BLOOD_Myeloma	Positive regulation of protein folding →	+0.144	+0.338	.001	<.001	3	3
OESOPHAGUS	Negative regulation of natural killer cell activation →	-0.150	-0.027	.001	.008	3	3
OESOPHAGUS	Regulation of heart rate by cardiac conduction →	-0.212	-0.027	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,102 associations by consensus.

Negative regulation of lymphocyte mediated immunity by IL26 expression — OESOPHAGUS

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