IL25

Across TCGA patient cohorts, IL25 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,627 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IL25-associated GO terms across cancer lineages are tRNA metabolic process, Establishment of protein localization to membrane, and Obsolete positive regulation of histone methylation. Each is linked with IL25 in more than 13 cancer types. Because this analysis shows association rather than direction, both IL25-to-partner and partner-to-IL25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by IL25-low versus IL25-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL25→partner) and Y-score (partner→IL25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA metabolic process →	+0.073	+0.046	<.001	<.001	3	13
STAD	Establishment of protein localization to membrane →	+0.071	+0.028	<.001	.006	3	12
STAD	Obsolete positive regulation of histone methylation →	+0.056	+0.037	<.001	.003	3	12
STAD	Regulation of DNA strand elongation →	+0.063	+0.067	<.001	.001	3	12
UCS	Obsolete histone H3-K4 methylation →	+0.071	+0.096	<.001	.002	1	14
STAD	Positive regulation of stem cell population maintenance →	+0.062	+0.045	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,627 associations by consensus.

tRNA metabolic process by IL25 expression — STAD

Explore this box plot interactively →