IL22RA2

Across TCGA patient cohorts, IL22RA2 mutation is significantly associated with the RNA expression of many other genes, with 1,257 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL22RA2-associated genes across cancer lineages are RNA5SP445, RPS29P21, and LCEP1. Each is linked with IL22RA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL22RA2-to-partner and partner-to-IL22RA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP445 grouped by IL22RA2-low versus IL22RA2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL22RA2→partner) and Y-score (partner→IL22RA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP445 →	+0.453	+4.973	<.001	.009	3	2
COAD	RPS29P21 →	+0.649	+4.237	.005	.008	3	2
LUSC	LCEP1 →	+0.121	+4.993	<.001	.003	3	2
UCEC	APOLD1 →	+0.937	+3.467	<.001	.002	3	1
UCEC	PTPN11 →	+0.603	+3.376	.008	.004	3	1
UCEC	ELMOD2 →	+0.628	+3.491	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,257 associations by consensus.

RNA5SP445 by IL22RA2 expression — BLCA

Explore this box plot interactively →