IL22RA2

Across TCGA cell cohorts, IL22RA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 225 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL22RA2-associated GO terms across cancer lineages are Platelet activation, Regulation of hemoglobin biosynthetic process, and Establishment or maintenance of transmembrane electrochemical gradient. Each is linked with IL22RA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IL22RA2-to-partner and partner-to-IL22RA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelet activation grouped by IL22RA2-low versus IL22RA2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL22RA2→partner) and Y-score (partner→IL22RA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Platelet activation →	+0.051	+0.117	<.001	.008	3	3
URINARY_TRACT	Regulation of hemoglobin biosynthetic process →	+0.121	+0.008	.002	.009	3	2
URINARY_TRACT	Establishment or maintenance of transmembrane electrochemical gradient →	+0.138	+0.008	.006	.009	3	2
URINARY_TRACT	Response to inactivity →	+0.081	+0.008	.008	.009	2	3
URINARY_TRACT	Regulation of sodium ion export across plasma membrane →	+0.191	+0.008	.003	.009	3	2
URINARY_TRACT	Positive regulation of sodium ion export across plasma membrane →	+0.191	+0.008	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 225 associations by consensus.

Platelet activation by IL22RA2 expression — BLOOD_Leukemia

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