IL22RA1

Across TCGA cell cohorts, IL22RA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,210 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IL22RA1-associated GO terms across cancer lineages are Positive regulation of protein localization to cell periphery, Negative regulation of protein catabolic process, and Antigen processing and presentation of peptide antigen via MHC class I. Each is linked with IL22RA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IL22RA1-to-partner and partner-to-IL22RA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to cell periphery grouped by IL22RA1-low versus IL22RA1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL22RA1→partner) and Y-score (partner→IL22RA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of protein localization to cell periphery →	+0.111	+1.604	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of protein catabolic process →	+0.081	+1.317	<.001	<.001	3	10
BREAST	Antigen processing and presentation of peptide antigen via MHC class I →	+0.207	+0.807	<.001	<.001	3	10
LARGE_INTESTINE	Response to progesterone →	+0.124	+1.222	<.001	.001	3	10
SOFT_TISSUE	Negative regulation of IP-10 production →	+1.500	+0.657	<.001	<.001	3	10
BREAST	Negative regulation of defense response →	+0.077	+0.706	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,210 associations by consensus.

Positive regulation of protein localization to cell periphery by IL22RA1 expression — PANCREAS

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