IL21

Across TCGA cell cohorts, IL21 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL21-associated genes across cancer lineages are TECRL. Each is linked with IL21 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL21-to-partner and partner-to-IL21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECRL grouped by IL21-low versus IL21-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL21→partner) and Y-score (partner→IL21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TECRL by IL21 expression — LARGE_INTESTINE

Explore this box plot interactively →