IL1RL2

Across TCGA patient cohorts, IL1RL2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,806 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IL1RL2-associated genes across cancer lineages are DIDO1, PDYN, and KLF5. Each is linked with IL1RL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL1RL2-to-partner and partner-to-IL1RL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL1RL2 versus DIDO1 in PDAC, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL1RL2→partner) and Y-score (partner→IL1RL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DIDO1 →	-0.391	-1.032	.007	.002	3	1
PDAC	PDYN →	+0.048	+0.880	.002	.004	3	1
PDAC	KLF5 →	-0.916	-1.225	.002	.003	3	1
PDAC	TLE5 →	-0.300	-0.820	.002	.003	3	1
PDAC	CYTH2 →	-0.697	-1.080	.007	.008	3	1
PDAC	HOXA2 →	-0.367	-1.181	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,806 associations by consensus.

IL1RL2 vs DIDO1 — PDAC

Explore this scatter interactively →