IL1RL1

Across TCGA pan-cancer cohorts, IL1RL1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IL1RL1 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher IL1RL1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL1RL1 expression acts as an unfavorable survival marker.

SCLC, LGG, and LUAD are the cancer types where IL1RL1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Median	All	0.164	0.625	.018	12	view →
LGG	OS	Median	All	0.337	0.812	.048	3	view →
LUAD	OS	Median	III,IV	0.250	0.685	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IL1RL1–SCLC (DFS)

Open the SCLC breakdown →