IL1RL1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IL1RL1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IL1RL1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL1RL1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IL1RL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC and UCEC are the cancer types where IL1RL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSQuartileAll0.8640.477.0213view →
UCECDFSMedianAll0.9260.739.0482view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

IL1RL1–HNSC (OS)

Kaplan–Meier survival curve for IL1RL1 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration