Across TCGA pan-cancer cohorts, IL1RL1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IL1RL1 data layer compared with 22 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IL1RL1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IL1RL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.
HNSC and UCEC are the cancer types where IL1RL1 mass-spec protein most reproducibly stratifies survival.